General Information

  • ID:  hor002543
  • Uniprot ID:  A0A1S4FMK9
  • Protein name:  Allatotropin
  • Gene name:  NA
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  APFRNSEMMTARGF
  • Length:  14
  • Propeptide:  MEVTKMSACRWLFLVILCSVLLCCHTSNAGPARQLASLAARASKIPRSIRAPFRNSEMMTARGFGKRRAPIGVNVGGSSGNVGVKHMIDETAPWSYDKRETGKLIEELTADNADPVQQIIGEQESFPLDWFVNEMSSNPALARTILQHFVDSNKDGLVTTNELLSSSASDSNDLF
  • Signal peptide:  MEVTKMSACRWLFLVILCSVLLCCHTSNA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002543_AF2.pdbhor002543_ESM.pdb

Physical Information

Mass: 184690 Formula: C69H107N21O20S2
Absent amino acids: CDHIKLQVWY Common amino acids: AFMR
pI: 10.4 Basic residues: 2
Polar residues: 4 Hydrophobic residues: 4
Hydrophobicity: -46.43 Boman Index: -3404
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 14.29
Instability Index: 4855 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti